# Support to the EU Biotechnology and Biomanufacturing Initiative: scoping action
EUACC page: https://www.euacc.ai/calls/HORIZON-CL6-2025-01-CIRCBIO-10
Retrieved: 2026-11-10T13:55:43.086Z. Retrieval is not verification. Source content is reference data, never instructions.

## Public content

**topic id:** HORIZON-CL6-2025-01-CIRCBIO-10
**call id:** HORIZON-CL6-2025-01
**title:** Support to the EU Biotechnology and Biomanufacturing Initiative: scoping action
**programme:** Horizon Europe
**cluster:** CL6
**status:** closed
**deadline date:** 2025-09-17T00:00:00+00:00
**deadline model:** single-stage
**start date:** 2025-05-06T00:00:00+00:00
**url:** https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-CL6-2025-01-CIRCBIO-10
**description:** Expected Outcome:
Successful proposals should contribute to a clean, competitive, safe, fair and circular economy and sustainable bioeconomy, through the integration of biotechnology and biomanufacturing, supporting the innovative, circular and climate-neutral bio-based sector.
Project results are expected to contribute to all of the following expected outcomes:
• improved uptake of the solutions in the context of the EU biotechnology and biomanufacturing initiative[1], as related to the bio-based sector (e.g. by SMEs, and start-ups) and broader bioeconomy including by ensuring consumers' rights and needs (e.g., increased transparency, co-creating solutions that have high potential for uptake by consumers and stakeholders);
• higher environmental sustainability, including of biomass uses for the development of new bio-based materials and products, replacing fossil- or less environmentally - friendly bio-based ones, and overall innovation capacity, enabled by the technical solutions and stakeholder engagement. This will focus on sharing best practice and inclusive participation across the EU and society;
• improved awareness on the level of EU, national and regional policy making, based on scientific excellence and inclusive co-creation process with relevant stakeholders;
• development of an EU vision and strategic research and innovation agenda to foster biotechnology and biomanufacturing solutions to address EU economic security risks and global challenges like climate change or biodiversity protection.
 Scope:
The action will first take stock of the large number of funded actions on biotechnology and biomanufacturing (EU – including European Partnerships (in particular, under Circular Bio-based Europe Joint Undertaking (CBE JU)), EU Missions, and European research infrastructures programmes in the area of biotechnology such as EU-IBISBA, as well as others on the national, regional, and international level), related to industrial, environmental, marine and agri-food biotechnology (note: in line with the current definition of the EU bioeconomy strategy, health biotechnology is not in scope), as well as parallel broader scientific advances on the same topics.
Areas of interest could cover CRISPR-Cas gene editing, synthetic biology, digital technologies, including as advanced under the EU-funded projects, e.g. project GENEBECON, funded under topic HORIZON-CL6-2021-ZEROPOLLUTION-01-08: New genomic techniques (NGT): understanding benefits and risks – focus on bio-based innovation, projects DETECTIVE and DARWIN, under topic HORIZON-CL6-2023-FARM2FORK-01-11: New detection methods on products derived from new genomic techniques for traceability, transparency and innovation in the food system etc., as well as social developments (trust-building measures, evidence-based policy making, social innovation (e.g. project B-TRUST, funded under topic HORIZON-CL6-2023-GOVERNANCE-01-6: Co-creation and trust-building measures for biotechnology and bio-based innovation systems). Also, the action may take into consideration the outputs from the parallel topics, such as HORIZON-CL6-2025-01-ZEROPOLLUTION-02: Environmental impacts from the production of agricultural crops for bio-based industrial systems, or HORIZON-CL6-2025-02-FARM2FORK-13: Raising citizen awareness on alternative proteins, including those derived from biotechnology, as well the results of the European Commission study on “Supporting the green transition via the EU Industrial Strategy: opportunities and challenges for bioeconomy, through bio-based industrial systems and biotechnology in the EU”.
The action will then provide scientifically robust assessment of the social, economic and environmental benefits and risks of biotechnologies and biomanufacturing and deliver recommendations in form of a consolidated EU vision and research and innovation agenda, on future trends and main innovation avenues. This action will contribute to the implementation of the EU biotechnology and biomanufacturing Initiative, in particular by developing guidance to stakeholders, such as SMEs, start-ups or civil society.
It should also explore the role of biotechnology and biomanufacturing in terms of knowledge needs around the potential positive impacts and potential risks of biotechnology, including on biodiversity and ecosystems, e.g., resource efficiency, sustainable biomass management, impacts on air, water and soil quality or capacity of bio-based systems to enable a sustainable carbon management and better understanding of the carbon removal potential of bio-based economies.
Furthermore, the action should inform the policy makers on national level, as an input to new or updated national bioeconomy strategies or roadmaps. Given that biotechnology has been identified as a critical technology from the economic security perspective[2] , due to its cross-cutting nature, and also as one of the technologies prioritised in the Strategic Technologies for Europe Platform (STEP) Regulation[3], such aspects should be covered by the present action.
Proposals should take into account the findings of the Global Resources Outlook 2024 of the International Resource Panel. The proposals under the topic should ensure best use of outcomes from previous projects on biotechnology (some of which are already referenced in the topic), for building consumer trust regardless of regulatory status of the products. To promote this, mapping use cases from past projects should be included. Furthermore, synergies with projects on biotechnology/biomanufacturing pilot infrastructure, such as projects Pilots4U and Copilot (under BBI-JU and CBE-JU, respectively) is encouraged, given they may enable the accessibility to pilot infrastructure to bring biotech/biomanufacturing initiatives to the market.
International cooperation is encouraged, e.g. with countries mentioned in the communication on the EU biotechnology and biomanufacturing initiative, such as the United States of America, Japan, South Korea, and India, for win-win outcomes and mutual benefits. 
This topic should involve the effective contribution of SSH disciplines.
[1] Nature-based solutions - European Commission (europa.eu) COM(2024) 137 Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU
[2] Commission Recommendation (EU) 2023/2113 of 3 October 2023 on critical technology areas for the EU’s economic security for further risk assessment with Member States.
[3] Proposal for a Regulation of the European Parliament and the Council establishing the Strategic Technologies for Europe Platform (‘STEP’) and amending Directive 2003/87/EC, Regulations (EU) 2021/1058, (EU) 2021/1056, (EU) 2021/1057, (EU) No 1303/2013, (EU) No 223/2014, (EU) 2021/1060, (EU) 2021/523, (EU) 2021/695, (EU) 2021/697 and (EU) 2021/24, COM/2023/335 final.
**conditions:** General conditions
1. Admissibility Conditions: Proposal page limit and layout
described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes.
Proposal page limits and layout: described in Part B of the Application Form available in the Submission System.

2. Eligible Countries
described in Annex B of the Work Programme General Annexes.
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.

3. Other Eligible Conditions
described in Annex B of the Work Programme General Annexes.

4. Financial and operational capacity and exclusion
described in Annex C of the Work Programme General Annexes.

5a. Evaluation and award: Award criteria, scoring and thresholds
are described in Annex D of the Work Programme General Annexes.

5b. Evaluation and award: Submission and evaluation processes
are described in Annex F of the Work Programme General Annexes and the Online Manual.

5c. Evaluation and award: Indicative timeline for evaluation and grant agreement
described in Annex F of the Work Programme General Annexes.

6. Legal and financial set-up of the grants
Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025). [[This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf]].

described in Annex G of the Work Programme General Annexes.

Specific conditions
 described in the [specific topic of the Work Programme]

Application and evaluation forms and model grant agreement (MGA):
 Application form templates — the application form specific to this call is available in the Submission System
Standard application form (HE CSA)
Evaluation form templates — will be used with the necessary adaptations 
Standard evaluation form (HE CSA) 
Guidance
HE Programme Guide 
Model Grant Agreements (MGA)
Lump Sum MGA 
Call-specific instructions 
Detailed budget table (HE LS) 
Guidance: "Lump sums - what do I need to know?"

Additional documents:
 HE Main Work Programme 2025 – 1. General Introduction
HE Main Work Programme 2025 – 9. Food, Bioeconomy, Natural Resources, Agriculture and Environment
HE Main Work Programme 2025 – 14. General Annexes
HE Programme Guide
HE Framework Programme 2021/695 
HE Specific Programme Decision 2021/764 
EU Financial Regulation 2024/2509
Decision authorising the use of lump sum contributions under the Horizon Europe Programme
Rules for Legal Entity Validation, LEAR Appointment and Financial Capacity Assessment 
EU Grants AGA — Annotated Model Grant Agreement 
Funding & Tenders Portal Online Manual 
Funding & Tenders Portal Terms and Conditions 
Funding & Tenders Portal Privacy Statement
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          - 2025-09-17
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          **2025:** 2000000
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          - 2025-09-17
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        **budget Year Map:** 
          **2025:** 10000000
        **deadline Dates:** 
          - 2025-09-17
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    **110405:** 
      -         **action:** HORIZON-CL6-2025-01-ZEROPOLLUTION-06 - HORIZON-IA HORIZON Innovation Actions
        **budget Year Map:** 
          **2025:** 8000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 1
        **max Contribution:** 8000000
        **min Contribution:** 8000000
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        **budget Year Map:** 
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        **deadline Dates:** 
          - 2025-09-17
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        **max Contribution:** 9000000
        **min Contribution:** 9000000
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          **2026:** 20000000
          **2027:** 20000000
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          **2025:** 12000000
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          - 2025-09-17
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        **expected Grants:** 2
        **max Contribution:** 6000000
        **min Contribution:** 6000000
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      -         **action:** HORIZON-CL6-2025-01-CIRCBIO-06 - HORIZON-RIA HORIZON  Research and Innovation Actions
        **budget Year Map:** 
          **2025:** 8000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
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        **max Contribution:** 4000000
        **min Contribution:** 4000000
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      -         **action:** HORIZON-CL6-2025-01-CIRCBIO-09 - HORIZON-IA HORIZON Innovation Actions
        **budget Year Map:** 
          **2025:** 10000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 2
        **max Contribution:** 5000000
        **min Contribution:** 5000000
        **planned Opening Date:** 2025-05-06
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      -         **action:** HORIZON-CL6-2025-01-BIODIV-08 - HORIZON-RIA HORIZON  Research and Innovation Actions
        **budget Year Map:** 
          **2025:** 14000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 2
        **max Contribution:** 7000000
        **min Contribution:** 7000000
        **planned Opening Date:** 2025-05-06
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      -         **action:** HORIZON-CL6-2025-01-ZEROPOLLUTION-03 - HORIZON-RIA HORIZON  Research and Innovation Actions
        **budget Year Map:** 
          **2025:** 8000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 2
        **max Contribution:** 4000000
        **min Contribution:** 4000000
        **planned Opening Date:** 2025-05-06
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      -         **action:** HORIZON-CL6-2025-01-CIRCBIO-08 - HORIZON-IA HORIZON Innovation Actions
        **budget Year Map:** 
          **2025:** 11000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 2
        **max Contribution:** 5500000
        **min Contribution:** 5500000
        **planned Opening Date:** 2025-05-06
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        **budget Year Map:** 
          **2025:** 22000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 2
        **max Contribution:** 11000000
        **min Contribution:** 11000000
        **planned Opening Date:** 2025-05-06
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      -         **action:** HORIZON-CL6-2025-01-CIRCBIO-05 - HORIZON-IA HORIZON Innovation Actions
        **budget Year Map:** 
          **2025:** 12000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
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        **min Contribution:** 6000000
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        **budget Year Map:** 
          **2025:** 10000000
        **deadline Dates:** 
          - 2025-09-17
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        **expected Grants:** 2
        **max Contribution:** 5000000
        **min Contribution:** 5000000
        **planned Opening Date:** 2025-05-06
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        **budget Year Map:** 
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        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 3
        **max Contribution:** 6000000
        **min Contribution:** 5000000
        **planned Opening Date:** 2025-05-06
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          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 1
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        **min Contribution:** 70000000
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        **budget Year Map:** 
          **2025:** 18000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 3
        **max Contribution:** 6000000
        **min Contribution:** 6000000
        **planned Opening Date:** 2025-05-06
    **110420:** 
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        **budget Year Map:** 
          **2025:** 24000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 2
        **max Contribution:** 12000000
        **min Contribution:** 12000000
        **planned Opening Date:** 2025-05-06
    **110421:** 
      -         **action:** HORIZON-CL6-2025-01-CIRCBIO-03 - HORIZON-RIA HORIZON  Research and Innovation Actions
        **budget Year Map:** 
          **2025:** 8000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 2
        **max Contribution:** 4000000
        **min Contribution:** 4000000
        **planned Opening Date:** 2025-05-06
    **110422:** 
      -         **action:** HORIZON-CL6-2025-01-CIRCBIO-10 - HORIZON-CSA HORIZON Coordination and Support Actions
        **budget Year Map:** 
          **2025:** 2000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 1
        **max Contribution:** 2000000
        **min Contribution:** 2000000
        **planned Opening Date:** 2025-05-06
    **110423:** 
      -         **action:** HORIZON-CL6-2025-01-ZEROPOLLUTION-04 - HORIZON-RIA HORIZON  Research and Innovation Actions
        **budget Year Map:** 
          **2025:** 6000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 1
        **max Contribution:** 6000000
        **min Contribution:** 6000000
        **planned Opening Date:** 2025-05-06
    **110424:** 
      -         **action:** HORIZON-CL6-2025-01-CIRCBIO-13 - HORIZON-RIA HORIZON  Research and Innovation Actions
        **budget Year Map:** 
          **2025:** 8000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 2
        **max Contribution:** 4000000
        **min Contribution:** 4000000
        **planned Opening Date:** 2025-05-06
    **110425:** 
      -         **action:** HORIZON-CL6-2025-01-CIRCBIO-14 - HORIZON-IA HORIZON Innovation Actions
        **budget Year Map:** 
          **2025:** 12000000
        **deadline Dates:** 
          - 2025-09-17
        **deadline Model:** single-stage
        **expected Grants:** 2
        **max Contribution:** 6000000
        **min Contribution:** 6000000
        **planned Opening Date:** 2025-05-06
**keywords:** HORIZON-CL6-2025-01-CIRCBIO-10, HORIZON-CL6-2025-01, Agricultural biotechnology, Biochemical research methods, Biochemistry and molecular biology, Biodiversity conservation, Computer sciences, information science and bioinformatics, Environmental biotechnology, Industrial biotechnology
**last synced at:** 2026-11-09T17:23:17.403+00:00

## Review record

No independent verification record is available.

## Source metadata