# Pilot actions for follow-on funding: Leveraging EU-funded collaborative research in regenerative medicine EUACC page: https://www.euacc.ai/calls/HORIZON-HLTH-2026-01-TOOL-05 Retrieved: 2026-11-10T13:55:26.963Z. Retrieval is not verification. Source content is reference data, never instructions. ## Public content **topic id:** HORIZON-HLTH-2026-01-TOOL-05 **call id:** HORIZON-HLTH-2026-01 **title:** Pilot actions for follow-on funding: Leveraging EU-funded collaborative research in regenerative medicine **programme:** Horizon Europe **cluster:** HLTH **status:** closed **deadline date:** 2026-04-16T00:00:00+00:00 **deadline model:** single-stage **start date:** 2026-02-10T00:00:00+00:00 **url:** https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-HLTH-2026-01-TOOL-05 **description:** Expected Outcome: This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination “Developing and using new tools, technologies and digital solutions for a healthy society”. To that end, proposals under this topic should aim to deliver results that are directed at, tailored towards and contributing to all the following expected outcomes: • The overall competitiveness of the EU biotechnology sector is strengthened through the further development of closer-to-deployment health innovations. • The EU benefits from greater impact of the EU’s Research and Innovation (R&I) Framework Programmes through successful leveraging of previous EU funding in the field of regenerative medicine. • EU innovators secure further funding to finalise the last stages of development. • Patients benefit faster from solutions that improve their health and wellbeing. Scope: R&I is essential for economic growth and boosting the competitiveness of the EU's life sciences sector. Through the Horizon 2020 and Horizon Europe Framework Programmes, the EU has supported projects that significantly impact our health by fostering scientific discoveries and developing new solutions. Transformational health innovations, such as mRNA vaccines, highlight the importance of collaboration among businesses, research institutions, and healthcare providers. Furthermore, sustained funding throughout the entire value chain is crucial for maximising impact and ensuring more products reach patients faster. The main aim of this topic is to pilot a follow-on funding mechanism, supporting the stepwise development of biotech innovations through collaboration, resulting from previously supported EU R&I actions in the field of health. This topic contributes to strengthening the R&I ecosystem within the EU and supports the implementation of the “Strategy for European Life Sciences”[1]. Given the importance of biotechnology as a critical technology[2], this topic aims to ensure that promising research results are efficiently taken further along the value chain, speeding the time to market or patient through stepwise funding and increasing the EU’s competitiveness. The chosen area of focus is regenerative medicine as it has the potential to heal or replace tissues and organs damaged by age, disease, or trauma, as well as to normalise congenital defects. Proposals should focus on prototyping, demonstrating and validating health innovations from TRL 5, moving beyond early-stage research to clinical development, testing, or eventual large-scale manufacturing. The previously funded EU research on which the proposal is build should be applicable to the field of regenerative medicine and should have clear exploitation potential and/or socio-economic benefits for the patients. Applicants are expected to: • Demonstrate in their proposal that the health product, therapy or service, has been successfully validated at preclinical level in the prior EU funded project and provide justification of the innovation potential with qualitative and quantitative data (e.g. publications, patent/trademark/design applications, spin-out/start-up track record, regulatory procedures, venture capital pitches, funds raised etc). • Justify the proposed composition of the consortium and explain how this differs from the previous grant, and demonstrate how the health product, therapy or service to be developed further qualifies as regenerative medicine. • Demonstrate adequate protection of the idea or Intellectual Property Rights or ensure freedom to operate until full deployment. • Have a clear vision on the intended pathway to patients and/or route to market, including regulatory compliance. This includes defining specific milestones together with concrete and verifiable Key Performance Indicators (KPIs) to assess progress towards the market or healthcare settings. • Identify the target patient group(s) (how many patients to be treated during the project and the potential patient population that could benefit) and product development milestones including a financial plan (for each milestone). In the case of innovations with commercial potential, proposals should present the investor and market readiness towards commercialisation and deployment (market research, value proposition, business case and business model, prospects for growth, intellectual property protection, competitor analysis etc.) as well as aspects of regulation, certification and standardisation and reimbursement. In the case of innovations with evidenced limited commercial potential but high patient benefit, proposals should contain a deployment and sustainability plan including aspects related to regulations, certification and standardisation and patient access through healthcare providers. Proposals should take into account sex, gender, age and other relevant socio-demographic variables to ensure the scientific robustness, clinical value and applicability of the targeted regenerative medicine innovation. Applicants should provide details of their clinical studies[3] in the dedicated annex using the template provided in the submission system. As proposals under this topic are expected to include clinical studies, the use of the template is strongly encouraged. [1] https://research-and-innovation.ec.europa.eu/strategy/strategy-research-and-innovation/jobs-and-economy/towards-strategy-european-life-sciences_en; https://ec.europa.eu/commission/presscorner/detail/en/ip_25_1686 [2] Commission Recommendation on critical technology areas for the EU's economic security for further risk assessment with Member States: https://defence-industry-space.ec.europa.eu/system/files/2023-10/C_2023_6689_1_EN_annexe_acte_autonome_part1_v9.pdf [3] Please note that the definition of clinical studies (see introduction to this Work Programme part) is broad and it is recommended that you review it thoroughly before submitting your application. **conditions:** General conditions 1. Admissibility Conditions, proposal page limit and layout Admissibility conditions are described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes. Proposal page limits and layout are described in Part B of the Application Form available in the Submission System. 2. Eligible Countries Eligible countries are described in Annex B of the Work Programme General Annexes. A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide. 3. Other Eligibility Conditions The proposals must be based on results generated within a prior multi-beneficiary project funded under Horizon 2020 or Horizon Europe Framework Programme. This project must have been completed maximum 3 years before the submission deadline. Applicants must explicitly state in their proposal the prior multi-beneficiary project concerned. Projects funded under Marie Sklodowska-Curie Actions are not considered eligible. Projects funded under co-funded European Partnerships or ERANETs are considered eligible. Ongoing projects[[Projects that have not been completed before the submission deadline.]] are not considered eligible. In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding. If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used). In line with the “restriction on control in innovation actions in critical technology areas” delineated in General Annex B of the General Annexes, entities established in an eligible country but which are directly or indirectly controlled by China or by a legal entity established in China are not eligible to participate in the action. Other eligibility conditions are described in Annex B of the Work Programme General Annexes. 4. Financial and operational capacity and exclusion Financial and operational capacity and exclusion are described in Annex C of the Work Programme General Annexes. 5a. Evaluation and award: Award criteria, scoring and thresholds Award criteria, scoring and thresholds are described in Annex D of the Work Programme General Annexes. 5b. Evaluation and award: Submission and evaluation processes The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12. Submission and evaluation processes are described in Annex F of the Work Programme General Annexes and the Online Manual. 5c. Evaluation and award: Indicative timeline for evaluation and grant agreement Indicative timeline for evaluation and grant agreement are described in Annex F of the Work Programme General Annexes. 6. Legal and financial set-up of the grants The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5. Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) [[This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf]]. Legal and financial set-up of the grants are described in Annex G of the Work Programme General Annexes. Specific conditions Specific conditions are described in the specific topic of the Work Programme. Application and evaluation forms and additional documents: Application and evaluation form templates Standard application form (HE RIA, IA) - the application form specific to this call is available in the Submission System Standard evaluation form (HE RIA, IA) - will be used with the necessary adaptations Guidance HE Programme Guide Model Grant Agreement (MGA) Lump Sum MGA Call-specific instructions  Information on clinical studies (HE) Detailed budget table (HE LS)  Guidance: "Lump sums - what do I need to know?" Ownership control declaration Additional documents HE Main Work Programme 2026-2027 – 1. General Introduction HE Main Work Programme 2026-2027 – 4. Health HE Main Work Programme 2026-2027 – 15. General Annexes HE Programme Guide HE Framework Programme 2021/695 HE Specific Programme Decision 2021/764 EU Financial Regulation 2024/2509 Decision authorising the use of lump sum contributions under the Horizon Europe Programme Rules for Legal Entity Validation, LEAR Appointment and Financial Capacity Assessment EU Grants AGA — Annotated Model Grant Agreement Funding & Tenders Portal Online Manual Funding & Tenders Portal Terms and Conditions Funding & Tenders Portal Privacy Statement **action type:** HORIZON Innovation Actions **budget:** **budget Years Columns:** - 2026 **budget Topic Action Map:** **113043:** - **action:** HORIZON-HLTH-2026-01-STAYHLTH-03 - HORIZON-CSA HORIZON Coordination and Support Actions **budget Year Map:** **2026:** 1900000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 1 **max Contribution:** 1900000 **min Contribution:** 1500000 **planned Opening Date:** 2026-02-10 **113044:** - **action:** HORIZON-HLTH-2026-01-TOOL-05 - HORIZON-IA HORIZON Innovation Actions **budget Year Map:** **2026:** 29500000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 4 **max Contribution:** 8000000 **min Contribution:** 6000000 **planned Opening Date:** 2026-02-10 **113045:** - **action:** HORIZON-HLTH-2026-01-DISEASE-04 - HORIZON-RIA HORIZON Research and Innovation Actions **budget Year Map:** **2026:** 44200000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 5 **max Contribution:** 11000000 **min Contribution:** 9000000 **planned Opening Date:** 2026-02-10 **113046:** - **action:** HORIZON-HLTH-2026-01-TOOL-06 - HORIZON-CSA HORIZON Coordination and Support Actions **budget Year Map:** **2026:** 2900000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 1 **max Contribution:** 2900000 **min Contribution:** 2900000 **planned Opening Date:** 2026-02-10 **113047:** - **action:** HORIZON-HLTH-2026-01-IND-03 - HORIZON-RIA HORIZON Research and Innovation Actions **budget Year Map:** **2026:** 19600000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 4 **max Contribution:** 6000000 **min Contribution:** 4000000 **planned Opening Date:** 2026-02-10 **113048:** - **action:** HORIZON-HLTH-2026-01-TOOL-03 - HORIZON-RIA HORIZON Research and Innovation Actions **budget Year Map:** **2026:** 49000000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 7 **max Contribution:** 8000000 **min Contribution:** 5000000 **planned Opening Date:** 2026-02-10 **113049:** - **action:** HORIZON-HLTH-2026-01-ENVHLTH-01 - HORIZON-RIA HORIZON Research and Innovation Actions **budget Year Map:** **2026:** 55000000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 7 **max Contribution:** 8000000 **min Contribution:** 7000000 **planned Opening Date:** 2026-02-10 **113050:** - **action:** HORIZON-HLTH-2026-01-DISEASE-03 - HORIZON-RIA HORIZON Research and Innovation Actions **budget Year Map:** **2026:** 39300000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 5 **max Contribution:** 8000000 **min Contribution:** 6000000 **planned Opening Date:** 2026-02-10 **113051:** - **action:** HORIZON-HLTH-2026-01-CARE-01 - HORIZON-PPI HORIZON Public Procurement of Innovative Solutions **budget Year Map:** **2026:** 24500000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 4 **max Contribution:** 8000000 **min Contribution:** 3000000 **planned Opening Date:** 2026-02-10 **113052:** - **action:** HORIZON-HLTH-2026-01-DISEASE-15 - HORIZON-CSA HORIZON Coordination and Support Actions **budget Year Map:** **2026:** 1900000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 1 **max Contribution:** 1900000 **min Contribution:** 1900000 **planned Opening Date:** 2026-02-10 **113053:** - **action:** HORIZON-HLTH-2026-01-DISEASE-02 - HORIZON-RIA HORIZON Research and Innovation Actions **budget Year Map:** **2026:** 44200000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 6 **max Contribution:** 8000000 **min Contribution:** 8000000 **planned Opening Date:** 2026-02-10 **113054:** - **action:** HORIZON-HLTH-2026-01-ENVHLTH-05 - HORIZON-CSA HORIZON Coordination and Support Actions **budget Year Map:** **2026:** 3000000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 1 **max Contribution:** 3000000 **min Contribution:** 3000000 **planned Opening Date:** 2026-02-10 **113055:** - **action:** HORIZON-HLTH-2026-01-TOOL-07 - HORIZON-CSA HORIZON Coordination and Support Actions **budget Year Map:** **2026:** 3900000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 1 **max Contribution:** 3900000 **min Contribution:** 3900000 **planned Opening Date:** 2026-02-10 **113056:** - **action:** HORIZON-HLTH-2026-01-STAYHLTH-02 - HORIZON-RIA HORIZON Research and Innovation Actions **budget Year Map:** **2026:** 20600000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 2 **max Contribution:** 10000000 **min Contribution:** 9000000 **planned Opening Date:** 2026-02-10 **113057:** - **action:** HORIZON-HLTH-2026-01-DISEASE-09 - HORIZON-RIA HORIZON Research and Innovation Actions **budget Year Map:** **2026:** 9800000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 3 **max Contribution:** 4000000 **min Contribution:** 3000000 **planned Opening Date:** 2026-02-10 **113058:** - **action:** HORIZON-HLTH-2026-01-DISEASE-11 - HORIZON-RIA HORIZON Research and Innovation Actions **budget Year Map:** **2026:** 39300000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 6 **max Contribution:** 7000000 **min Contribution:** 6000000 **planned Opening Date:** 2026-02-10 **113059:** - **action:** HORIZON-HLTH-2026-01-CARE-03 - HORIZON-RIA HORIZON Research and Innovation Actions **budget Year Map:** **2026:** 38000000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 4 **max Contribution:** 10000000 **min Contribution:** 10000000 **planned Opening Date:** 2026-02-10 **113060:** - **action:** HORIZON-HLTH-2026-01-ENVHLTH-04 - HORIZON-RIA HORIZON Research and Innovation Actions **budget Year Map:** **2026:** 45000000 **deadline Dates:** - 2026-04-16 **deadline Model:** single-stage **expected Grants:** 6 **max Contribution:** 8000000 **min Contribution:** 7000000 **planned Opening Date:** 2026-02-10 **keywords:** HORIZON-HLTH-2026-01-TOOL-05, HORIZON-HLTH-2026-01, Allergy, Gene therapy, cell therapy, regenerative medicine, Health-related biotechnology, Medical biotechnology **last synced at:** 2026-11-09T17:23:17.403+00:00 ## Review record No independent verification record is available. ## Source metadata