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This round is closed. Synced from the EU Funding & Tenders Portal on 9 November 2026.
Based on projects the EU funded on the same subject in this programme.
ZeroFDevelopment of verified safe and sustainable PFAS-free coatings for food packaging and upholstery textile applications
HORIZON-CL4-2022-RESILIENCE-01-23 · 2023 · Official record ↗
SSbD4CheMSafe and Sustainable by Design framework for the next generation of Chemicals and Materials
HORIZON-CL4-2023-RESILIENCE-01-21 · 2024 · Official record ↗
PLANETSPlasticizers, fLame-retardants and surfactANts: new alternatives validating the safE and susTainable by deSign approach
HORIZON-CL4-2024-RESILIENCE-01-24 · 2024 · Official record ↗
M2DESCOComputational Multi-Models Enabled Design of Safe & Sustainable Multi-Component High-Entropy Coatings
HORIZON-CL4-2023-RESILIENCE-01-23 · 2024 · Official record ↗
iLCA4SSbDIntegration of Life Cycle Assessment methodologies for Safe and Sustainable by Design
HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-52 · 2026 · Official record ↗
PINKProvision of Integrated Computational Approaches for Addressing New Markets Goals for the Introduction of Safe-and-Sustainable-by-Design Chemicals and Materials
HORIZON-CL4-2023-RESILIENCE-01-23 · 2024 · Official record ↗
ANALYSTSTRENGTHENING THE INTEGRATED APPROACH OF HOLISTIC IMPACT ASSESSMENTS FOR SAFE AND SUSTAINABLE BY DESIGN PLASTIC VALUE CHAIN
HORIZON-CL4-2023-RESILIENCE-01-22 · 2024 · Official record ↗
TORNADONEW ROUTES OF SAFE AND SUSTAINABLE BY DESIGN WATER AND OIL REPELLENT BIOBASED COATINGS
HORIZON-CL4-2022-RESILIENCE-01-23 · 2023 · Official record ↗
Each one links to its EU funding record and the partners it works with: a starting list for building a consortium.
Projects are expected to contribute to the following outcomes:
PFAS are a large class of substances used in a wide range of applications (for instance, as adhesives, coatings, lubricants, sealants, surfactants), for their technical and/or safety functions (e.g., water and oil repellence, antiadhesion, thermal & chemical stability)[6]. Nevertheless, PFAS have been detected in groundwater, surface water and soil, the remediation of which is extremely problematic[7],[8]. Their accumulation in the environment has been linked to negative effects for the wildlife and the human health, including carcinogenic, mutagenic, reprotoxic and toxic effects for the endocrine system[9]. In January 2023, five national authorities submitted to the European Chemicals Agency (ECHA) a PFAS restriction dossier to ban the manufacture, placing on the market and use of PFAS as a chemical class in all uses, with few exemptions[10].
The Commission initiative for SSbD sets a framework which should be a reference in the proposal. The new alternatives to be developed should meet the technical functions required in the specific applications and align with such framework.
Proposals should address at least one industrial application and should develop one or more new chemical substances or technologies to replace existing PFAS used, according to abovementioned applications and functions, in one of the following areas:
All actors along the value chain should be involved to ensure the new substance has a clear use case, market and potential to grow.
Multidisciplinary research activities should address all of the following:
Proposals should indicate to which chapters of the Strategic Research and Innovation Plan for chemicals and materials[12] they will contribute.
Proposals submitted under this topic should include a business case and exploitation strategy.
In accordance with the SSbD framework, this topic requires the effective demonstration of the added value of the outcomes to protect human health and the environment, e.g. in the fields of biodiversity protection, indoor and /or outdoor air quality.
Collaboration with existing Open Innovation Test Beds (OITBs)[13] should be explored - where relevant.
International collaboration is encouraged.
The challenge of developing PFAS alternatives should also cooperate with relevant topics under other clusters and calls of Horizon Europe (e.g. HORIZON-CL4-2021-RESILIENCE-01-08[14], HORIZON-CL4-2022-RESILIENCE-01-23[15], HORIZON-CL6-2023-ZEROPOLLUTION-02-2-two-stage[16], Horizon 2020 LC-GD-8-1-2020[17]), including topics under the Chips Joint Undertaking and the Clean Hydrogen Joint Undertaking (e.g. HORIZON-JTI-CLEANH2-2024-05-02: Development of non-fluorinated components for fuel cells and electrolysers). Proposals should specifically allocate the necessary resources for collaboration with the other relevant projects.
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Activities are expected to start at TRL 3-4 and achieve TRL 6-7 by the end of the project – see General Annex B.
[1] Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:02006R1907-20231201
[2] https://ec.europa.eu/environment/ecolabel/the-ecolabel-scheme.html
[3] https://ec.europa.eu/environment/publications/proposal-ecodesign-sustainable-products-regulation_en
[4] https://commission.europa.eu/energy-climate-change-environment/standards-tools-and-labels/products-labelling-rules-and-requirements/sustainable-products/ecodesign-sustainable-products-regulation_en
[5] See documents defining the SSbD framework and criteria on: https://ec.europa.eu/info/research-and-innovation/research-area/industrial-research-and-innovation/key-enabling-technologies/advanced-materials-and-chemicals_en
[6] This list of applications and functions are not exhaustive, unless explicitly mentioned.
[7] https://www.eea.europa.eu/en/european-zero-pollution-dashboards/indicators/pfas-contamination-and-soil-remediation-signal
[8] PFAS in European seas (Signal) (europa.eu)
[9] https://doi.org/10.2903/j.efsa.2022.e200418
[10] Per- and polyfluoroalkyl substances (PFAS) - ECHA (europa.eu)
[11] The use of (gaseous) PFAS in air conditioning is outside the scope of this call.
[12] https://ec.europa.eu/info/research-and-innovation/research-area/industrial-research-and-innovation/key-enabling-technologies/advanced-materials-and-chemicals_en
[13] https://ec.europa.eu/info/research-and-innovation/research-area/industrial-research-and-innovation/sustainable-production-processes_en
[14] https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/horizon-cl4-2021-resilience-01-08
[15] https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/horizon-cl4-2022-resilience-01-23
[16] https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/horizon-cl6-2023-zeropollution-02-2-two-stage
[17] https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/lc-gd-8-1-2020
1. Admissibility Conditions: Proposal page limit and layout
Applicants submitting a proposal under the blind evaluation pilot (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E).
described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes.
Proposal page limits and layout: described in Part B of the Application Form available in the Submission System.
2. Eligible Countries
described in Annex B of the Work Programme General Annexes.
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.
3. Other Eligible Conditions
described in Annex B of the Work Programme General Annexes.
4. Financial and operational capacity and exclusion
described in Annex C of the Work Programme General Annexes.
5a. Evaluation and award: Award criteria, scoring and thresholds
This topic is part of the blind evaluation pilot under which first stage proposals will be evaluated blindly.
are described in Annex D of the Work Programme General Annexes.
5b. Evaluation and award: Submission and evaluation processes
are described in Annex F of the Work Programme General Annexes and the Online Manual.
5c. Evaluation and award: Indicative timeline for evaluation and grant agreement
described in Annex F of the Work Programme General Annexes.
6. Legal and financial set-up of the grants
Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) [[This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf]].
described in Annex G of the Work Programme General Annexes.
described in the [specific topic of the Work Programme]
Application and evaluation forms and model grant agreement (MGA):
Application form templates — the application form specific to this call is available in the Submission System
Stage 1: Standard application form (HE RIA IA Stage 1 BLIND)
Stage 2: 2025 RIA/IA Application form: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/temp-form/af/af_he-ria-ia_v9.0_en.pdf
Evaluation form templates — will be used with the necessary adaptations
Strage 1: Standard evaluation form (HE RIA, IA and CSA Stage 1 BLIND)
Stage 2: 2025 RIA/IA Evaluation form: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/temp-form/ef/ef_he-ria-ia_v3.0_en.pdf
Guidance
HE Programme Guide
Model Grant Agreements (MGA)
Lump Sum MGA 
Call-specific instructions 
2025 Detailed budget table: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/common/temp-form/af/detailed-budget-table_he-ls-euratom_v3.3_en.xlsm
Information on financial support to third parties (HE) 
Information on clinical studies (HE) 
Guidance: "Lump sums - what do I need to know?"
Additional documents:
HE Main Work Programme 2025 – 1. General Introduction
HE Main Work Programme 2025 – 7. Digital, Industry and Space
HE Main Work Programme 2025 – 14. General Annexes
HE Programme Guide
HE Framework Programme 2021/695
HE Specific Programme Decision 2021/764
EU Financial Regulation 2024/2509
Decision authorising the use of lump sum contributions under the Horizon Europe Programme
Rules for Legal Entity Validation, LEAR Appointment and Financial Capacity Assessment 
EU Grants AGA — Annotated Model Grant Agreement 
Funding & Tenders Portal Online Manual 
Funding & Tenders Portal Terms and Conditions 
Funding & Tenders Portal Privacy Statement
Confirm the current call documents and submission conditions with the funding authority.
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